US scientists discovered a new antibiotic family in soil samples that could be useful in combating difficult-to-treat infections – the BBC’s news portal wrote.
New compounds may be able to fight with difficult-to-treat bacterial infections, including MRSA (methicillin-resistant Staphylococcus aureus), “super bacteria”, in a study published by Rockefeller University researchers in the current issue of the journal Nature Microbiology.
Drug-resistant infections, caused by so-called super bacteria, are one of the world’s biggest health threats, causing about 700,000 deaths annually.
New York scientists have been researching soil samples after microorganisms, as millions of tiny creatures in the soil cling to and produce compounds that might be useful in the fight against pathogens.
Genetic sequencing, that is, the organisms found in more than a thousand soil samples have been studied by mapping the entire hereditary substance of the organism.
When several malacidin compounds were discovered in several samples, they felt something important. The material was tested in MRSA-infected rats. The wounds on their skin were missed.
Scientists are now working to increase the effectiveness of the drug. It is hoped that healing medicines can be developed for human infections.
“It’s impossible to tell when a new-discovered antibiotic family can come to clinical trials, but whether or not to go to this stage,” said Sean Brady, head of research.
Colin Garner, of the British Antibiotic Research Institute, is good news that new antibiotics have been found against so-called Gram-positive bacteria such as MRSA, but the need for Gram-negative bacteria would be most needed.
“The latter are difficult to curb, and the number of antibiotics is growing among them. These bacteria cause pneumonia, septicemia, urinary tract infection and skin infections,” Garner told BBC.